Visuals » Movies

  • Whole organ imaging of healthy and NTN kidneys
    The surface and the complex vascular organization (CD31) of an entire kidney is shown via optical clipping into the kidney volume. Additionally, both the Bowman's capsule (SHG) and the surrounding kidney tubules (autofluorescence) are shown. Glomerular capillaries of untreated mice are normally shaped, while NTN treated animals exhibit vessel damage.
    J Am Soc Nephrol. 2016 Aug 3. pii: ASN.2016020232.
  • 3D-reconstruction of an ECi cleared heart
    Autofluorescence of the heart muscle tissue offers detailed structural information about the external and internal organ structure. The vasculature of the heart was specifically stained via CD31. Clipping of the 3D model allows a view inside the right ventricle showing its intracardial papillary muscles and chordae tendinae as well as the ventricular septum.
    J Am Soc Nephrol. 2016 Aug 3. pii: ASN.2016020232.
  • 3D-reconstruction of an ECi cleared Calvaria
    ECi-cleared calvarial bone is visualized via its autofluorescence signal. Additionally, the entire blood vessel system is labeled and imaged via specific endothelial antibody staining (CD31).
    J Am Soc Nephrol. 2016 Aug 3. pii: ASN.2016020232.
  • Z-Stack through a whole mouse lung
    Right lobe cleared with THF/DBE. Alveoli are stained with FITC-BSA and bronchi and bronchioles were visualized by autofluorescence.
  • 3D reconstructed mouse lung
    Right lobe cleared with THF/DBE. Alveoli are stained with FITC-BSA and bronchi and brochnioles are visualized by their autofluorescence.
  • Migration of neutrophils in the bone marrow of a mobilized mouse
    Coming soon
    Nat Methods. 2015 May;12(5):445-52.
  • Long-term observation of neutrophil migration in situ.
    Coming soon
    Nat Methods. 2015 May;12(5):445-52.
  • Motility of PMN in G-CSF-mobilized mice pre-treated with anti-Cxcr2
    Coming soon
    Blood 2011 Apr 21;117(16):4349-57. doi: 10.1182/blood-2010-09-308387. Epub 2011 Jan 11.
  • PMN immigration into a bone marrow blood sinus
    Coming soon
    Blood 2011 Apr 21;117(16):4349-57. doi: 10.1182/blood-2010-09-308387. Epub 2011 Jan 11.
  • Motility of PMN in G-CSF-mobilized mice
    Coming soon
    Blood 2011 Apr 21;117(16):4349-57. doi: 10.1182/blood-2010-09-308387. Epub 2011 Jan 11.
  • Dendritic Cells Dragging Conidia in Collagen
    A well resolved dendritic cell drags a conidium through a distance of up to 9 µm. The conidium, however, is not phagocytosed by the cell. The observation was made over 3 h with one frame every 30 s.
    PLoS Pathog. 2007 Feb;3(2):e13.
  • RAW Macrophages with Candida Albicans Yeasts in Collagen
    A few RAW macrophages can be seen here carrying Candida albicans yeasts. A large yeast is taken up by a cell at 30 min and is pulled up towards the cell. The observation was made over a period of 2 h with one frame every 30 s.
    PLoS Pathog. 2007 Feb;3(2):e13.