Whole organ imaging of healthy and NTN kidneys
The surface and the complex vascular organization (CD31) of an entire kidney is shown via optical clipping into the kidney volume. Additionally, both the Bowman's capsule (SHG) and the surrounding kidney tubules (autofluorescence) are shown. Glomerular capillaries of untreated mice are normally shaped, while NTN treated animals exhibit vessel damage.
J Am Soc Nephrol. 2016 Aug 3. pii: ASN.2016020232.